Protagen Protein Services GmbH
Abstract: Developing and producing recombinant biopharmaceuticals in mammalian cells requires unambiguous monitoring of HCPs impurities. Immunoassays are still the method of choice for release testing, however, peptide analysis by MS has been proven to be a powerful tool box by providing complementary data for HCP characterization. We show that MS supports the data interpretation of methods for antisera characterization, like high resolution 2D PAGE/ Immunoblotting to demonstrate antisera coverage.
Description:
Category: Analytical
Type: Biologics
Contact: Dr. Marcus Mreyen ([email protected])